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Macronutrients and food reward
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If you see one bright red swan, you are not likely to give up a theory that says that all swans are white; you will instead go looking for the person who painted it. Imre Lakatos Much is being said on this subject. Bet many are getting pretty fed up by now. But I still…
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A closer look at adiponectin
Whether insulin or leptin or adiponectin or PPAR gamma or NF KB or a bajillion cytokines are the proximate mediators of obesity or atherosclerosis is hardly the point, is it? Kurt G. Harris MD Although biochemistry can be marvelously exiting we must not lose sight of the bigger picture. It is increasingly unlikely that any…
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Leptin and local cellular hunger – uniting the theories
Leptin About 15 years ago the 167 amino acid peptide hormone leptin was discovered by Jeffrey M. Friedman and colleagues through work with genetic mouse models. It is primarily expressed in adipose tissue and there is thus a close correlation between the blood level of leptin and the size of the fat tissue. A small fat…
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