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There is a blogging battle going on. Dueling, are Anthony Colpo and Michael Eades. It seems Eades has Colpo cornered, and in the last round Eades pulled the «Popper’s black swan» card. Inspired the aged but beautiful writings of Popper, I thought…
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The trouble with insulin resistance, part III
I was in way over my head starting to ramble on about insulin resistance hoping I would identify a causal link. But I feel I should finish what I’ve started. The trouble with insulin resistance is that it is so…
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Ketogenic diet and resistance exercise
Not to brag, but new study out here.Hope someone will find it interesting.
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More trouble with insulin resistance
I’ll make an attempt to sum up some of my previous rambling. When we talk about insulin resistance it is often important to include information on which tissues we are talking about. When insulin resistance is measured by clamp technique…
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Just a small reminder
”…low carbohydrate diet sets the stage for a significant loss of lean tissue as the body recruits amino acids from muscle to maintain blood glucose via gluconeogenesis.” Exercise Physiology, Mcardle,…
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By the way…
New exiting study in Diabetes Care. Abstract here. It seems that if you put overweight people on a resistance exercise program three days a week for 16 weeks, they will lose about two kilos of muscle mass, if they are…
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The trouble with insulin resistance
Been thinking a lot about insulin resistance lately. Most importantly how a resistance in different tissues might cause different pathologies. Gary Taubes must have been thinking a lot about insulin resistance as well. Way more than me anyway. The following…
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Big fat lies
Hanna Sutter from Big Fat Lies in Daily Mail: «For the past 30 years we’ve been told to eat less and exercise more, to cut back on calories and on saturated fat and, on the whole, we’re doing it. Our…
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Cancer as a metabolic disease
Is cancer a metabolic disease? In principle, there are few chronic diseases more easily preventable than cancer. Seyfried and Shelton 2010 A new and important article in Nutrition and Metabolism makes a case for cancer as predominately a metabolic disease.…
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It’s your choice
A recent study by Yancy et al shows that going on a low fat calorie restricted diet in combination with the shady orlistat drug results in the same weight loss as a low carbohydrate diet over a 48 week period.…
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Great blog and great former blogger current twitterer
Dave Dixon here:http://twitter.com/sparkofreasonand Petro Dobromylskyj here:http://high-fat-nutrition.blogspot.com/
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The tide is turning
Ronald M Krauss, former Senior Advisor to the National Cholesterol Education Program, actively involved with the American Heart Association, former Chairman of the Nutrition Committee, has in collaboration with Siri-Tarino Patty, Sun Qi and B. H. Frank conducted meta-analysis of prospective cohort studies evaluating…
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The devil is in the details
Sherlock Holmes is back on the screen. A master of deduction and a firm believer in science, he is showing us the devil is in the details. But even data acquired through vigorous scientific studies need to be exposed to…
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Local cellular hunger
I once wrote a short paper about menstrual disturbances in female athletes. Menstrual disorders seem to be more prevalent in athletes than sedentary controls and more prevalent in sports emphasizing leanness. Elite athletes also have higher menarche age compared to…
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About hunger
Much has been said about hunger. The sensation is often considered largely under cognitive control. An overweight person seeking counselling is asked to eat less, despite claiming to already be hungry most of the time. Hunger is in this case…
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A scale model of obesity
Whatever the individual cause of obesity is, in the absolute majority of cases, carbohydrate restriction works effectively at reducing adipose tissue weight. This is a common observation in most human and animal studies. Carbohydrate restriction for the most part works…
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Does it fit the facts?
Explaining overweight through the effect of insulin and glucose metabolism on fat tissue can so far only be termed a hypothesis. It is a hypothesis build primarily on physiological knowledge. The next logical step is to check if the hypothesis…
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The second question provides the answer
On our way to understand overweight we have (that is I have, but I thought you should be included) defined overweight as excess storage of energy in fat tissue and we asked the obvious; what factors control the storage of…
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The important question
By defining overweight as excess storage of energy in fat tissue (and consequently to little use of energy from the same tissue), we are only one simple question away from understanding what causes overweight and obesity, and ultimately how to…
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Defining overweight
The first thing I’m going to do in this blog is to explain what causes overweight and obesity. I’ll also explain what can be done about it. It will not be the old dogma of eating less and exercising more.…
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