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Angående konflikter og sannheter
Om sannheter Hvis du er interessert i helse og vil vite hvem som har rett og hvem som tar feil med henhold til helse, må du forstå det følgende. Noen ting i verden er svart/hvitt, rett og galt. Noen ting er fullstendig uten nyanser. Når én ting er rett, er alt annet galt. Det finnes sannheter…
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Hva er egentlig problemet med rødt kjøtt? (In Norwegian)
istockphoto Mandag 31. januar la Nasjonalt råd for ernæring frem rapporten, ”Kostråd for å fremme folkehelsen og forebygge kroniske sykdommer.” Rapporten er en vitenskapelig gjennomgang av kostens påvirkning på en rekke sykdommer og helsetilstander, og gir konkrete råd om forebygging. Blant rådene er en anbefaling om restriksjon i inntaket av rødt kjøtt. Begrunnelsen er at…
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What is the best exercise for fat loss? Part IV
The biasI have this theory. In the last post I concluded that there is sufficient data for recommending high intensity exercise in favor of low intensity for fat loss. Admittedly, the data in support of this is not strong. It is there, but I would not bet my life on it yet. I might be…
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Play
Let’s face it, we are social animals. Being forced to solitary living is considered a punishment and rightly so. As social animals we play, both as young and as adults. Play builds social skills, it makes sure our neurons are properly connected and it builds and protects our body. With ever growing focus on lifestyle…
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What if…
“And then, one Thursday, nearly two thousand years after one man had been nailed to a tree for saying how great it would be to be nice to people for a change, a girl sitting on her own in a small cafe in Rickmansworth suddenly realized what it was that had been going wrong all…
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Like talking to a brick wall
To disagree only as much as the evidence permitsJamie Scott, the Primal Muse hit a brick wall recently. Metaphorically speaking, of course. The wall’s embodiment was a narrow minded and rude purveyor of what to the untrained eye might look like science. Scientific disagreements are fascinating because science as a “reality exploring tool” does not…
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A closer look at adiponectin
Whether insulin or leptin or adiponectin or PPAR gamma or NF KB or a bajillion cytokines are the proximate mediators of obesity or atherosclerosis is hardly the point, is it? Kurt G. Harris MD Although biochemistry can be marvelously exiting we must not lose sight of the bigger picture. It is increasingly unlikely that any…
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High fat diets and endurance exercise performance
«When first thrown wholly upon a diet of reindeer meat, it seems inadequate to properly nourish the system, and there is an apparent weakness and inability to perform severe exertive fatiguing journeys. But this soon passes away in the course of two or three weeks.« From Stephen D. Phinney (2004) The above excerpt is from the…
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Energy in, energy out and the fairies in the back of my garden
Science philosopher Karl Popper proposed that science is easily performed. A theory must be falsifiable and the role of science is to prove a theory wrong. On the other hand if a theory resists constant attempts of falsification the probability of it being true increases. This is a very satisfying, concrete and mechanistic view of…
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A tribute to the bloggers
During my student years I read the standard scientific method curriculum book, “The Structure of Scientific Revolutions” by Thomas S. Kuhn. In it, Kuhn writes about scientific paradigms and paradigm shifts. Although he was criticized for using the word “paradigm” in a rather inconsistent manner, it was still marvelous reading. What I learned then was…
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The frustrations of a low carber
Science moves in mysteries ways. Despite its goal to be an objective tool describing the world as it is, science, when used by us humans, is not objective. Once a result, mathematical formula or any data acquired is interpreted the objectivity seizes to exist. And this is exactly how it should be. Data are worthless if…
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The strange case of chronic fatigue syndrome
«Undoubtedly, the perverse use of CFS, to impose a psychiatric definition for ME/CFS by associating it with fatigue syndromes, has delayed research, the discovery of effective treatment(s), and care and support for those with this illness.« Hooper 2007 Having a background and an interest in metabolism I am intrigued by reports about chronic fatigue syndrome.…
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Ketogenic diets and the treatment of epilepsy
”But this kind does not go out except by prayer and fasting” Matthew 17:21 and Mark 9:29 “One who is confronted with the task of controlling seizures in a person with epilepsy grasps at any straw. When, some six or eight years ago, an osteopathic practitioner in Michigan stated that fasting would cure epilepsy, this…
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A nutrition paradox
By denying scientific principles, one may maintain any paradox. Galileo Galilei Istockphoto If an overweight person…
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Leptin and local cellular hunger – uniting the theories
Leptin About 15 years ago the 167 amino acid peptide hormone leptin was discovered by Jeffrey M. Friedman and colleagues through work with genetic mouse models. It is primarily expressed in adipose tissue and there is thus a close correlation between the blood level of leptin and the size of the fat tissue. A small fat…
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The causality of insulin resistance
There seem to be two large somewhat competing hypotheses trying to explain the causality of insulin resistance (as measured at a whole body level). The lipotoxicity hypothesis, explains to us how insulin sensitivity is reduced in tissues when too much fat builds up in the specific tissue cells; likely caused by high serum levels of…
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Colpo, Eades and black swans.
There is a blogging battle going on. Dueling, are Anthony Colpo and Michael Eades. It seems Eades has Colpo cornered, and in the last round Eades pulled the «Popper’s black swan» card. Inspired the aged but beautiful writings of Popper, I thought of some other nice quotes fitting for the nutrition debate. Enjoy! Here are some from…
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The trouble with insulin resistance, part III
I was in way over my head starting to ramble on about insulin resistance hoping I would identify a causal link. But I feel I should finish what I’ve started. The trouble with insulin resistance is that it is so bloody hard to point to the exact cause at a cellular and molecular level. I’ve…
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Cancer as a metabolic disease
Is cancer a metabolic disease? In principle, there are few chronic diseases more easily preventable than cancer. Seyfried and Shelton 2010 A new and important article in Nutrition and Metabolism makes a case for cancer as predominately a metabolic disease. Research has shown that one of the key features of cancers is an impaired or…
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Local cellular hunger
I once wrote a short paper about menstrual disturbances in female athletes. Menstrual disorders seem to be more prevalent in athletes than sedentary controls and more prevalent in sports emphasizing leanness. Elite athletes also have higher menarche age compared to non elite athlete controls. Menstrual disorders increase the risk of low bone mineral density, stress…
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